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OSILODROSTAT (oh SIL oh DROE stat) is used to treat Cushing's disease. It is used when surgery is not an option or has not worked well enough.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician about the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medicine with any of the following medications:
-cisapride
-dofetilide
-dronedarone
-pimozide
-thioridazine
This medicine may also interact with the following medications:
-carbamazepine
-certain antivirals for HIV or hepatitis
-certain medicines for fungal infections like ketoconazole, itraconazole, or posaconazole
-clarithromycin
-other medicines that prolong the QT interval (an abnormal heart rhythm)
-phenobarbital
-rifampin
-theophylline
-tizanidine
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. You may need blood work done while you are taking this medicine.
Do not breast-feed an infant while taking this medicine or for 1 week after stopping it.
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If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
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Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-acne in women
-excessive hair growth on the face or body
-loss of appetite
-signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast, irregular heartbeat; palpitations; feeling faint or lightheaded; falls; breathing problems
-signs and symptoms of low potassium like muscle cramps; muscle pain; chest pain; dizziness; feeling faint or lightheaded, falls; palpitations; breathing problems; or fast, irregular heartbeat
-swelling of the ankles, feet, hands
-unusually weak or tired
-vomiting
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
-headache
-nausea
-tiredness
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children.
Store this medicine at room temperature between 15 to 30 degrees C (59 to 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date on the label.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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