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LONAFARNIB (loe na far nib) treats certain types of genetic disorders such as Hutchinson-Gilford progeria syndrome. It is not a cure.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medicine by mouth with water. Take it with food. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medicine. Swallow the capsules whole. You may open the capsule and put the contents in 5 to 10 mL of Ora Blend SF, Ora-Plus, orange juice, or 1 to 2 teaspoons of applesauce. Do not take with juice that contains grapefruit or Seville oranges. Seville oranges may also be called bitter or sour oranges. Swallow the drug mixture within 10 minutes of mixing. Do not chew the drug or applesauce. Keep taking it unless your health care provider tells you to stop.
Talk to your health care provider about the use of this drug in children. While it may be prescribed for children as young as 12 months for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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This medicine has many drug interactions. Talk to your health care provider if you have questions.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.
This drug may increase your risk of getting an infection. Call your health care provider for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Your vision may be tested before and during use of this drug. Tell your health care provider right away if you have any change in your eyesight.
Do not become pregnant while taking this drug. Women should inform their health care provider if they wish to become pregnant or think they might be pregnant. There is potential for serious harm to an unborn child. Talk to your health care provider for more information.
This drug may make it more difficult to get pregnant/father a child. Talk to your health care provider if you are concerned about your fertility.
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If you miss a dose, take it as soon you can up to 8 hours before your next scheduled dose. If it is less than 8 hours before your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your doctor or health care professional as soon as possible:
-anemia, low red blood cell counts (trouble breathing; feeling faint, lightheaded, falls; unusually weak or tired)
-changes in vision
-high calcium levels (increased thirst; increased urination; constipation; muscle weakness; nausea or vomiting; unusually weak or tired)
-high potassium levels (chest pain; fast, irregular heartbeat; muscle weakness)
-infection (fever, chills, cough, sore throat, pain or trouble passing urine)
-kidney injury (trouble passing urine or change in the amount of urine)
-lack or loss of appetite
-liver injury (dark yellow or brown urine; general ill feeling or flu-like symptoms; loss of appetite, right upper belly pain; unusually weak or tired, yellowing of the eyes or skin)
-low potassium levels (trouble breathing; chest pain; dizziness; fast, irregular heartbeat; feeling faint or lightheaded, falls; muscle cramps or pain)
-thrombocytopenia
-weight loss
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
-cough
-diarrhea
-headache
-joint pain
-muscle pain
-tiredness
-stomach pain
-vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F).
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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