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    • VERZENIO

    • QTY 56
    • 100 MG
    • Tablet

ABEMACICLIB (a BEM a SYE klib) targets proteins in cancer cells and stops the cancer cells from growing. It treats certain types of breast cancer.

VERZENIO Lifestyle Interactions

  • Abemaciclib 100mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not eat grapefruit or drink grapefruit juice while on Abemaciclib therapy without approval from your healthcare provider. Grapefruit products may increase the blood levels of Abemaciclib. This may increase the risk of side effects including diarrhea, pain or swelling in your arms or legs, chest pain, fast heartbeat, breathing problems, signs of infection including fever or chills, cough, sore throat, pain or trouble passing urine, dark yellow or brown urine, general ill feeling or flu-like symptoms, light-colored stools, loss of appetite, nausea, right upper belly pain, unusually weak or tired, or yellowing of the eyes or skin.
    • Notes for Professionals: Advise patients to avoid grapefruit products during abemaciclib treatment due to the potential for increased abemaciclib exposure. Abemaciclib is a CYP3A4 substrate and grapefruit is a strong CYP3A inhibitor. Coadministration with another strong CYP3A4 inhibitor increased the relative potency adjusted unbound AUC of abemaciclib plus its active metabolites (M2, M18, and M20) by 2.5-fold in cancer patients.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.