-
VENETOCLAX (ven et oh klax) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat chronic lymphocytic leukemia, small lymphocytic lymphoma, and acute myelogenous leukemia.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
-
Take this medicine by mouth with food and a glass of water. Follow the directions on the prescription label. Do not cut, crush, or chew this medicine. Do not take with grapefruit juice or eat Seville oranges or starfruit. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
-
This medicine may interact with the following medications:
-bosentan
-calcium channel blockers like diltiazem and verapamil
-captopril
-carvedilol
-certain antibiotics like azithromycin, erythromycin, and clarithromycin
-certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, and voriconazole
-certain medicines for irregular heart beat like amiodarone, dronedarone, and quinidine
-certain medicines for seizures like carbamazepine and phenytoin
-ciprofloxacin
-conivaptan
-cyclosporine
-digoxin
-efavirenz
-etravirine
-everolimus
-felodipine
-grapefruit products, Seville oranges, or starfruit
-indinavir
-live virus vaccines
-lopinavir
-modafinil
-nafcillin
-quercetin
-ranolazine
-rifampin
-ritonavir
-sirolimus
-St. John’s wort
-telaprevir
-ticagrelor
-warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
-
This medicine can cause serious reactions. To reduce your risk you will need to take other medicine(s) before treatment with this medicine. Take your medicine as directed.
You may need blood work done while you are taking this medicine.
Drink plenty of fluids while you are taking this medicine.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
Do not become pregnant while taking this medicine or for 30 days after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 1 week after stopping it.
This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.
-
If you miss a dose, take it as soon as you can. If your next dose is to be taken in less than 16 hours, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses. If you vomit after a dose, do not take another dose; take the next day's dose at the usual time.
-
Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding
-signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eyes, gums, or nose
-signs and symptoms of infection like fever or chills; cough; sore throat; or pain when urinating
-signs and symptoms of tumor lysis syndrome like nausea, vomiting, confusion, shortness of breath, seizures, irregular heartbeat, dark urine, tiredness, muscle pain, and/or joint pain
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-back pain
-constipation
-diarrhea
-dizziness
-headache
-stomach pain
-swelling of the ankles, feet, hands
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
-
Keep out of the reach of children and pets.
Store at or below 30 degrees C (86 degrees F). Keep this medication in the original container. Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or have expired:
-Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health team. If it is safe to put it in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
En Español
