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    • URYL (Brand for UROGESIC-BLUE)

METHENAMINE; SODIUM ACID PHOSPHATE; METHYLENE BLUE; HYOSCYAMINE (meth EN a meen; SOE dee um  AS id  FOS fate; METH uh leen  bloo; hye oh SYE a meen) is used to stop the pain, burning, or discomfort caused by infection or irritation of the urinary tract. This medicine is not an antibiotic. It will not cure a urinary tract infection.

URYL (Brand for UROGESIC-BLUE) Lifestyle Interactions

  • Urinary Antiseptic/Antispasmodic/Anti-inflammatory, Oral tablet

    • Interaction: Caffeine-containing Foods/Beverages
    • Severity: Major
    • Notes for Consumers: Limit excessive Caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Sympathomimetics and avoid medicines containing additional Caffeine whenever possible. Examples of Sympathomimetics include stimulants or weight loss drugs like Amphetamine, Adderall, Dexedrine, Fastin, and Tenuate. Sympathomimetics also include some cough and cold products containing Pseudoephedrine (example Sudafed), Phenylephrine, or Phenylpropanolamine (PPA) and also herbal weight loss products containing ephedra or Ma huang. Taking a high amount of Caffeine with the listed drugs can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, or other side effects.
    • Notes for Professionals: Sodium phosphates should be used with caution in patients using concomitant medications that lower the seizure threshold like psychostimulants.

  • Urinary Antiseptic/Antispasmodic/Anti-inflammatory, Oral tablet

    • Interaction: Food
    • Severity: Moderate
    • Notes for Consumers: You may need to follow some dietary instructions while taking this drug to help control bacteria in the urine. This drug requires an acidic urine to be most effective. Certain foods, like milk and most fruits or fruit juices, might interfere with the best action of this drug in preventing urine infections. Ask your prescriber if you should avoid or limit any of these foods in the diet during your treatment. Orange juice and other fruit juices are not helpful at making the urine more acidic.
    • Notes for Professionals: Methenamine should theoretically not be administered concurrently with food or beverages that may alter urinary pH, such as milk products and most fruits. These agents may cause the urine to become alkaline and reduce the effectiveness of methenamine by inhibiting its conversion to formaldehyde. Orange juice is not a reliable urinary acidifier and should not be used to ensure urine acidification; citric acid may actually raise urine pH if taken in large amounts.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.