Do not take this medication with any of the following:
-Metyrapone
-Vaccines or toxoids
This medication may interact with the following:
-Amphotericin B
-Antibiotics like clarithromycin, erythromycin, and troleandomycin
-Aspirin and aspirin-like drugs
-Barbiturates like phenobarbital
-Carbamazepine
-Certain medications for fungal infections, like itraconazole or ketoconazole
-Cholestyramine
-Cholinesterase inhibitors like donepezil, galantamine, neostigmine, physostigmine, pyridostigmine, rivastigmine, and tacrine
-Cyclosporine
-Digoxin
-Diuretics
-Female hormones, like estrogens or progestins and birth control pills
-Isoniazid
-Medications for diabetes
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-Phenytoin
-Rifampin
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Cushing syndrome—increased fat around the midsection, upper back, neck, or face, pink or purple stretch marks on the skin, thinning, fragile skin that easily bruises, unexpected hair growth
-High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision
-Increase in blood pressure
-Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
-Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
-Mood and behavior changes—anxiety, nervousness, confusion, hallucinations, irritability, hostility, thoughts of suicide or self-harm, worsening mood, feelings of depression
-New or worsening eye pain, redness, irritation, or discharge
-Stomach bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds
-Sudden eye pain or change in vision such as blurry vision, seeing halos around lights, vision loss
-Swelling of the ankles, hands, or feet
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
-Blurry vision
-Headache
-Pain, redness, or irritation at injection site
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.