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    • TORISEL (Brand for TEMSIROLIMUS)

    • QTY 1
    • FDN 30MG/3
    • VIAL

TEMSIROLIMUS (TEM sir OH li mus) is a drug that alters immune system response in the body. It is used to treat renal cell cancer.

TORISEL (Brand for TEMSIROLIMUS) Lifestyle Interactions

  • Temsirolimus 25mg/1mL, Solution for injection

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take Temsirolimus with Grapefruit Juice. Grapefruit Juice may increase the levels of Temsirolimus in your body and side effects from Temsirolimus may be worse.
    • Notes for Professionals: Avoid consumption of grapefruit or grapefruit juice with temsirolimus due to increased plasma concentrations of the primary active metabolite of temsirolimus (sirolimus). Temsirolimus is a CYP3A4 substrate and grapefruit juice is a strong CYP3A4 inhibitor. Coadministration with another strong CYP3A4 inhibitor did not significantly affect temsirolimus exposure, but increased the AUC and Cmax of sirolimus by 3.1-fold and 2.2-fold, respectively.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.