TOPOTECAN HCL (Generic for HYCAMTIN)

TOPOTECAN (TOE poe TEE kan) is a chemotherapy drug. It is used to treat lung cancer, ovarian cancer, and cervical cancer.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

This medicine is for infusion into a vein. It is usually given by a health care professional in a hospital or clinic setting.
 
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

-amiodarone
-azithromycin
-captopril
-carvedilol
-certain medications for fungal infections like ketoconazole and itraconazole
-clarithromycin
-conivaptan
-cyclosporine
-dronedarone
-eltrombopag
-erythromycin
-felodipine
-grapefruit juice
-lopinavir
-quercetin
-quinidine
-ranolazine
-ritonavir
-ticagrelor
-verapamil

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
 
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
 
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
 
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
 
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
 
Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
 
In females, this medicine may make it more difficult to get pregnant. This medicine has also caused reduced sperm counts in some men. This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.

It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing difficulties
-diarrhea
-signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
-signs of decreased red blood cells - unusually weak or tired, feeling faint or lightheaded, falls
-signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine
 
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-hair loss
-headache
-loss of appetite
-nausea, vomiting
-stomach pain

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Keep out of the reach of children.

This drug is usually given in a hospital or clinic and will not be stored at home.

In rare cases, this medicine may be given at home. If you are using this medicine at home, you will be instructed on how to store this medicine. Throw away any unused medicine after the expiration date on the label.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.