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LEVOTHYROXINE (lee voe thye ROX een) treats low thyroid levels (hypothyroidism) in your body. It works by replacing a thyroid hormone normally made by the body. Thyroid hormones play an important role in your overall health. They help support metabolism and energy levels.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth. Follow the directions on the prescription label. Take at the same time each day. It is best to take on an empty stomach, at least 30 minutes to 1 hour before breakfast. Take antacids containing aluminum or magnesium, simethicone, bile acid sequestrants, calcium carbonate, sodium polystyrene sulfonate, ferrous sulfate, sevelamer, lanthanum, or sucralfate at a different time of day than this medication. Take these products 4 hours BEFORE or 4 hours AFTER this medication. Do not take your medication more often than directed.
For Tirosint-SOL: You may place the solution in a small amount of (5 or 10 mL or 1 to 2 teaspoonfuls) of water if needed. Do not mix with any other liquid.
For Thyquidity: Take directly into the mouth. Do not add to water.
Talk to your care team about the use of this medication in children. While this medication may be prescribed for children as young as newborns for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-Amiodarone
-Antacids, vitamins, or other products that contain aluminum, calcium, iron, or magnesium
-Calcium supplements
-Carbamazepine
-Certain medications for depression
-Certain medications to treat cancer
-Cholestyramine
-Clofibrate
-Colesevelam
-Colestipol
-Digoxin
-Female hormones, like estrogens and birth control pills, patches, rings, or injections
-Ketamine
-Lanthanum
-Liquid nutrition products like Ensure
-Lithium
-Medications for colds and breathing difficulties
-Medications for diabetes
-Medications for hyperthyroidism
-Medications or dietary supplements for weight loss
-Methadone
-Niacin
-Orlistat
-Oxandrolone
-Phenobarbital or other barbiturates
-Phenytoin
-Rifampin
-Sevelamer
-Simethicone
-Sodium polystyrene sulfonate
-Soy isoflavones
-Steroid medications like prednisone or cortisone
-Sucralfate
-Testosterone
-Theophylline
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Do not switch brands of this medication unless your care team agrees with the change. Ask questions if you are uncertain.
You will need regular exams and occasional blood tests to check the response to treatment. If you are receiving this medication for an underactive thyroid, it may be several weeks before you notice an improvement. Check with your care team if your symptoms do not improve.
It may be necessary for you to take this medication for the rest of your life. Do not stop using this medication unless your care team advises you to.
This medication can affect blood sugar levels. If you have diabetes, check your blood sugar as directed.
You may lose some of your hair when you first start treatment. With time, this usually corrects itself.
If you are going to have surgery, tell your care team that you are taking this medication.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Anxiety, nervousness
-Excessive sweating or sensitivity to heat
-Fever
-Heart palpitations—rapid, pounding, or irregular heartbeat
-Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
-Irregular menstrual cycles or spotting
-Severe diarrhea
-Tremors or shaking
-Trouble sleeping
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Changes in appetite
-Hair loss
-Headache
-Nausea
-Vomiting
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Tirosint-SOL: Store at 25 degrees C (77 degrees F); may store at 15 to 30 degrees C (59 to 86 degrees F) for a short time. Keep this medication in the original container. Throw away any unused medication 15 days after opening the pouch or after the expiration date, whichever is first.
Thyquidity: Store at 20 to 25 degrees C (68 to 77 degrees F). Throw away any unused medication 8 weeks after opening the bottle or after the expiration date, whichever is first.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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