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    • SUNITINIB MALATE (Generic for SUTENT)

SUNITINIB (soo NI ti nib) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat specific digestive tract tumors called GISTs, advanced kidney cancer, and certain pancreatic neuroendocrine tumors.

SUNITINIB MALATE (Generic for SUTENT) Lifestyle Interactions

  • Sunitinib Malate 12.5mg, Oral capsule

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take Grapefruit or Grapefruit juice with sunatinib. Side effects from sunatinib may get worse if you take grapefruit or grapefruit juice. Contact your health care provider if you experience increased fatigue, weakness, fever, diarrhea, nausea, mouth sores, vomiting, abdominal pain, increased blood pressure, fluid retention, rash, dry skin or other skin problems, headache, joint or muscle pain, cough, shortness of breath, loss of appetite, or unusual bleeding or bruising, or any other unusual effects.
    • Notes for Professionals: Advise patients to avoid taking sunitinib with grapefruit juice due to increased sunitinib exposure, which may increase the risk of QT prolongation or other side effects. Sunitinib is a CYP3A4 substrate and grapefruit juice is a strong CYP3A4 inhibitor. Coadministration with another strong CYP3A4 inhibitor increased exposure to sunitinib and its primary active metabolite by 51%.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.