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ASCIMINIB (as kim i nib) targets proteins in cancer cells and stops the cancer cells from growing. It treats chronic myelogenous leukemia.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medicine by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medicine. Swallow the tablets whole. Take it on an empty stomach, at least 2 hours before and 1 hour after food. Keep taking it unless your health care provider tells you to stop.
Do not take this medicine with grapefruit juice.
Talk to your health care provider about the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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-certain antibiotics like clarithromycin or telithromycin
-certain antivirals for HIV or hepatitis
-certain medicines for fungal infections like itraconazole, ketoconazole, posaconazole, or voriconazole
-grapefruit juice
-midazolam
-repaglinide
-rosiglitazone
-warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your health care provider for regular checks on your progress. It may be some time before you see the benefit from this medicine.
You may need blood work done while you are taking this medicine.
This medicine may increase your risk of getting an infection. Call your health care provider for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
Do not become pregnant while taking this medicine or for 1 week after stopping it. Women should inform their health care provider if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care provider for more information. Do not breast-feed an infant while taking this medicine and for 1 week after the last dose.
This medicine may make it more difficult to get pregnant. Talk to your health care provider if you are concerned about your fertility.
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It is important not to miss any doses. Talk to your health care provider about what to do if you miss a dose.
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Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions (skin rash; itching or hives; swelling of the face, lips, or tongue)
-blood clot (chest pain; shortness of breath; pain, swelling, or warmth in the leg)
-heart attack (trouble breathing; pain or tightness in the chest, neck, back or arms; unusually weak or tired)
-heart failure (trouble breathing; fast irregular heartbeat; sudden weight gain; swelling of the ankles, feet, hands; unusually weak or tired)
-Increase in blood pressure
-infection (fever, chills, cough, sore throat, pain or trouble passing urine)
-low red blood cell counts (trouble breathing; feeling faint; lightheaded, falls; unusually weak or tired)
-pancreatitis (stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting, fast heartbeat)
-stroke (changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm, or leg; trouble walking; dizziness; loss of balance or coordination)
-unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
-bone pain
-diarrhea
-joint pain
-muscle pain
-nausea
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medicine in the original container. Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:
-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, empty the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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