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NITROGLYCERIN (nye troe GLI ser in) treats pain caused by small tears in the skin near the rectal area. It works by relaxing the blood vessels, which decreases pressure around the rectal area. It belongs to a group of medications called nitrates.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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This medication is for rectal use only. Do not take by mouth. Follow the directions on the prescription label. Use exactly as directed. Cover a finger with plastic-wrap or surgical glove. Use the dosing guide on the medication box to measure the dose. With the ointment on the covered finger, insert into anal canal up to the first finger joint. After application, throw away the finger covering. Wash hands after applying ointment.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Medications used to treat erectile dysfunction like sildenafil, tadalafil, and vardenafil
-Riociguat
This medication may also interact with the following:
-Alteplase
-Aspirin
-Certain migraine medications like ergotamine and dihydroergotamine (DHE)
-Heparin
-Medications for high blood pressure
-Other medications used to treat angina
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Tell your care team if you feel your medication is no longer working.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.
Do not treat yourself for coughs, colds, or pain while you are taking this medication without asking your care team for advice. Some ingredients may increase your blood pressure.
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If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Headache, unusual weakness or fatigue, shortness of breath, nausea, vomiting, rapid heartbeat, blue skin or lips, which may be signs of methemoglobinemia
-Increased pressure around the brain—severe headache, blurry vision, change in vision, nausea, vomiting
-Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
-Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue
-Worsening chest pain (angina)—pain, pressure, or tightness in the chest, neck, back, or arms
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Dizziness
-Flushing
-Headache
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Close tightly after each use. Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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