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    • KISQALI

    • QTY 63
    • 600 MG/DAY
    • Tablet

RIBOCICLIB (rye boe SYE klib) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat breast cancer.

KISQALI Lifestyle Interactions

  • Ribociclib 200mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take ribociclib with grapefruit or grapefruit juice. Taking these together may increase ribociclib levels and ribociclib side effects.
    • Notes for Professionals: Avoid the concomitant use of ribociclib and grapefruit or grapefruit juice; the systemic exposure of ribociclib may be increased resulting in an increase in ribociclib-related adverse reactions. Ribociclib is a CYP3A4 substrate and grapefruit is a strong CYP3A inhibitor. Coadministration with another strong CYP3A4 inhibitor increased the ribociclib AUC and Cmax values by 3.2-fold and 1.7-fold, respectively, in healthy volunteers.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.