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IBRANCE Lifestyle Interactions
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Palbociclib 125mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Major• Notes for Consumers: Grapefruit Juice may increase the actions of Palbociclib. Side effects from Palbociclib may get worse if you eat Grapefruit or drink Grapefruit Juice. Do not take Palbociclib and Grapefruit Juice together without talking to your health care provider. Discuss any new or worsening side effects like infection, nausea, diarrhea, or weakness with your health care provider.• Notes for Professionals: Avoid concomitant use of palbociclib, a CYP3A4 substrate and grapefruit juice, a strong CYP3A4 inhibitor, as palbociclib plasma exposure may increase.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.