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    • EPLERENONE (Generic for INSPRA)

    • QTY 90
    • 25 MG
    • Tablet

EPLERENONE (e PLER en one) is a diuretic. It helps you make more urine and to lose salt and excess water from your body. It treats high blood pressure and heart failure. It can treat heart damage after a heart attack.

EPLERENONE (Generic for INSPRA) Lifestyle Interactions

  • Eplerenone 25mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Severe
    • Notes for Consumers: Do not take these drugs together. Discuss possible alternative treatment options with your prescriber. Taking these drugs together can increase the amount of Eplerenone in your blood and may cause your blood pressure to be too low or increase the amount of potassium in your blood. When there is too much potassium in the blood it can cause muscle weakness or an abnormal heart rhythm.
    • Notes for Professionals: Concomitant use of grapefruit or grapefruit juice and eplerenone is contraindicated. Grapefruit potently inhibits the hepatic CYP3A4 isoenzyme and may increase serum eplerenone concentrations by about 25% and, hence, can increase the risk of developing eplerenone-induced hyperkalemia and hypotension.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.