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COARTEM Lifestyle Interactions
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Artemether 20mg, Lumefantrine 120mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Moderate• Notes for Consumers: Do not take Artemether and Grapefruit juice together without approval from your prescriber. Grapefruit juice may increase blood levels of Artemether, which may increase side effects. Contact your prescriber immediately if you experience side effects while taking these drugs together.• Notes for Professionals: Grapefruit juice is a inhibitor and artemether a substrate of the CYP3A4 isoenzyme; therefore, coadministration may lead to increased artemether concentrations. Concomitant use warrants caution due to the potential for increased side effects.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.