CAMPATH

ALEMTUZUMAB (AL em TOOZ oo mab) is a monoclonal antibody. Campath is used to treat B cell chronic lymphocytic leukemia. Lemtrada is used to treat multiple sclerosis.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

The medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting. You may receive acetaminophen (Tylenol), diphenhydramine (Benadryl), or corticosteroids before your infusion to help decrease side effects related to the medicine. Your doctor may also give you antibiotics to help prevent infections.
 
A special MedGuide will be given to you if you are receiving this medicine for multiple sclerosis. Be sure to read this information carefully each time.
 
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

This medicine may interact with the following medications:
-vaccines

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Your condition will be monitored carefully while you are receiving this medicine. Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.
You may need blood work while you are taking this medicine.
This medicine may increase your risk of getting an infection. Call your health care provider for advice if you get a fever, chills, sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your health care provider if you notice any unusual bleeding.
In some patients, this medicine may cause a serious brain infection that may cause death. If you have any problems seeing, thinking, speaking, walking, or standing, tell your health care provider right away. If you cannot reach your health care provider, urgently seek another source of medical care.
This medicine can cause a blood clotting problem called thrombotic thrombocytopenic purpura (TTP). TTP is a rare but serious medical condition that can be deadly. Get medical help right away if you have purple spots on your skin or in your mouth; yellowing of the eyes or skin; general ill-feeling or flu-like symptoms; stomach pain; unusually weak or tired; fever; chest pain; trouble breathing; pain, swelling, or warmth in leg; confusion; severe headaches; trouble speaking; trouble walking; changes in vision; or trouble passing urine.
Do not become pregnant while taking this medicine or for 4 months after the last dose. Women should inform their health care provider if they wish to become pregnant or think they might be pregnant. There is potential for serious harm to an unborn child. Talk to your health care provider for more information. Do not breast-feed an infant while taking this medicine or for at least 3 months after the last dose.
This medicine may make it more difficult to get pregnant or father a child. Talk to your health care provider if you are concerned about your fertility.

It is important not to miss a dose. Call your doctor or health care professional if you are unable to keep an appointment.

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-changes in vision
-chest pain
-confusion
-dizziness
-loss of memory
-palpitations
-problems with balance, talking, or walking
-red or dark brown urine
-signs and symptoms of a stroke like changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of balance or coordination
-signs and symptoms of infection like fever; chills; cough; sore throat; pain or trouble passing urine
-signs and symptoms of meningitis such as stiff neck; sensitivity to light; headache; drowsiness; fever; nausea; vomiting; rash
-swelling of the ankles, feet, hands
-unusual bleeding or bruising
-unusually weak or tired
-vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-constipation
-diarrhea
-fatigue
-mild headache
-nausea
-trouble sleeping

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This medicine is given in a hospital or clinic. It will not be stored at home.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.