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    • BRUKINSA

    • QTY 30
    • 80 MG
    • Capsule

ZANUBRUTINIB (zan ue broo ti nib) treats lymphoma. It works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.

BRUKINSA Lifestyle Interactions

  • Zanubrutinib 80mg, Oral capsule

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take Grapefruit juice or grapefruit-containing foods and Zanubrutinib together without talking to your health care provider. Side effects may get worse if you drink Grapefruit juice or consume grapefruit-containing foods while taking Zanubrutinib. Contact your prescriber immediately if you experience fever or chills, cough, sore throat, pain or trouble passing urine, unusual bleeding or bruising, chest pain, dizziness, fast or irregular heartbeat, palpitations, feeling faint or lightheaded, or breathing problems.
    • Notes for Professionals: Advise patients to avoid grapefruit juice or grapefruit-containing foods while taking zanubrutinib. Coadministration may result in increased zanubrutinib exposure and toxicity (e.g., infection, bleeding, and atrial arrhythmias). Zanubrutinib is a CYP3A4 substrate; grapefruit juice is a strong CYP3A4 inhibitor. The AUC of zanubrutinib was increased by 278% when coadministered with another strong CYP3A4 inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.