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ENZALUTAMIDE (EN za LOO ta mide) blocks the effect of the male hormone called testosterone. It treats certain types of prostate cancer.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medicine by mouth. Take it as directed on the prescription label at the same time every day. Do not cut, crush or chew this medicine. Swallow the tablets whole. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your health care provider tells you to stop.
Talk to your health care provider about the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medicine with any of the following medications:
-artemether
-certain antivirals for HIV or hepatitis such as atazanavir, daclatasvir, doravirine, elbasvir; grazoprevir, fostemsavir, lopinavir, nelfinavir, paritaprevir, rilpivirine, ritonavir, and tipranavir
-certain medicines for fungal infections such as isavuconazonium and voriconazole
-lonafarnib
-lorlatinib
-lurasidone
-praziquantel
-ranolazine
This medicine may also interact with the following medications:
-alfentanil
-certain medicines for seizures such as carbamazepine, phenobarbital, phenytoin
-clopidogrel
-cyclosporine
-ergot alkaloids such as dihydroergotamine, ergotamine
-fentanyl
-gemfibrozil
-midazolam
-omeprazole
-pimozide
-quinidine
-rifabutin
-rifampin
-rifapentine
-St. John's Wort
-sirolimus
-tacrolimus
-warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.
This medicine should not be used in women. Men should not father a child while taking this medicine and for 3 months after stopping it. There is potential for serious harm to an unborn child. Talk to your health care provider for more information.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
-changes in vision
-confusion
-falls
-loss of memory
-pain or tightness in the chest, neck, back, or arms
-seizures
-stroke (changes in vision; confusion; trouble speaking or understanding; severe headaches; sudden numbness or weakness of the face, arm or leg; trouble walking; dizziness; loss of balance or coordination)
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):
-blood in the urine
-diarrhea
-dizziness
-edema (sudden weight gain; swelling of the ankles, feet, hands or other unusual swelling; trouble breathing)
-headache
-hot flashes (flushing of skin, increased sweating)
-joint pain
-lack or loss of appetite
-pain, tingling, numbness in the hands or feet
-unusually weak or tired
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children and pets.
Store between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:
-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, empty the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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