VUMERITY

Diroximel Fumarate 231mg, Oral capsule, gastro-resistant

Alcohol

· Severity: Moderate

· Notes for Consumers: Do not drink Alcohol at the same time as taking your Diroximel Fumarate doses. Drinking Alcohol at the same time as taking a dose of this medicine may decrease the effects of the drug. Do not drive or operate machinery if you have been drinking alcoholic beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, or that this drug is not working as well for you, contact your health care provider immediately.

· Notes for Professionals: Alcohol should not be taken at the time of a diroximel fumarate delayed-release capsule dose. The active metabolite of diroximel fumarate is monomethyl fumarate, or MMF. The mean peak plasma MMF concentration decreased by 9% and 21%, when the dose was coadministered with 240 mL of 5% v/v and 40% v/v of alcohol, respectively. Total MMF exposure is not altered; coingestion of ethanol does not induce "dose dumping".

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>