• Image of Vivelle-Dot medication Image of Vivelle-Dot medication
    • ESTRADIOL (TWICE WEEKLY) (Generic for VIVELLE-DOT)

    • QTY 24
    • 0.05MG/24H
    • PATCH TDSW
    • Near  77381

ESTRADIOL (es tra DYE ole) reduces the number and severity of hot flashes due to menopause. It may also help relieve the symptoms of menopause, such as vaginal irritation, dryness, or pain during sex. It can also be used to prevent osteoporosis after menopause. It works by increasing levels of the hormone estrogen in the body. This medication is an estrogen hormone.


ESTRADIOL (TWICE WEEKLY) (Generic for VIVELLE-DOT) Lifestyle Interactions

  • Clindamycin Phosphate 1.2%, Tretinoin 0.025%, Topical gel

    Interaction: Grapefruit juice
    Severity: Moderate
    Notes for Consumers: Although an interaction is possible, Clindamycin and Grapefruit Juice may be used together with caution. Side effects may get worse if you take these drugs together. Discuss any new or worsening side effects, such as diarrhea, abdominal pain, and vomiting, with your health care provider.
    Notes for Professionals: Monitor for an increase in clindamycin-related adverse reactions with coadministration of grapefruit juice as concurrent use may increase clindamycin exposure. Clindamycin is a CYP3A4 substrate; grapefruit juice is a strong inhibitor of CYP3A4.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.