• No image available for this medication

    • EMTRICITABINE-TENOFOVIR DISOP (Generic for TRUVADA)

EMTRICITABINE; TENOFOVIR DISOPROXIL FUMARATE (em trye SYE ta been; ten OF oh vir dye soe PROX il FUE ma rate) helps manage the symptoms of HIV infection. It may also be used for PrEP (pre-exposure prophylaxis), which lowers the risk of getting HIV through sex. It works by limiting the spread of HIV in the body. It is a combination of two antiretroviral medications. This medication is not a cure for HIV or AIDS and it may still be possible to spread HIV to others while taking it. It does not prevent other sexually transmitted infections (STIs).

EMTRICITABINE-TENOFOVIR DISOP (Generic for TRUVADA) Lifestyle Interactions

  • Emtricitabine 200mg, Tenofovir Disoproxil Fumarate 300mg, Oral tablet

    • Interaction: Marijuana
    • Severity: Moderate
    • Notes for Consumers: The effects of marijuana may be increased and side effects may get worse if it is combined with this medicine. Do not drive or operate machinery until you know how this combination will affect you. Contact your health care provider right away if you notice slurred speech, confusion, severe drowsiness, increased heart rate, or any other new or unusual side effects.
    • Notes for Professionals: The pharmacokinetic parameters of anti-retroviral medications (anti-retroviral non-nucleoside reverse transcriptase inhibitors (NNRTIs), anti-retroviral nucleoside reverse transcriptase inhibitors (NRTIs), anti-retroviral nucleotide reverse transcriptase inhibitors, and anti-retroviral protease inhibitors) metabolized through the CYP isoenzyme system are slightly altered by smoked and oral marijuana. Despite this interaction, marijuana is not expected to adversely affect anti-retroviral efficacy.However, the incidence of marijuana associated adverse effects may change following coadministration with anti-retroviral drugs. Many anti-retrovirals are inhibitors of CYP3A4, an isoenzyme partially responsible for the metabolism of marijuana's most psychoactive compound, delta-9-tetrahydrocannabinol (Delta-9-THC). When given concurrently with anti-retrovirals, the amount of Delta-9-THC converted to the active metabolite 11-hydroxy-delta-9-tetrahydrocannabinol (11-OH-THC) may be reduced. These changes in Delta-9-THC and 11-OH-THC plasma concentrations may result in an altered marijuana adverse event profile.

  • Emtricitabine 200mg, Tenofovir Disoproxil Fumarate 300mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Moderate
    • Notes for Consumers: Side effects might get worse if you take this drug with grapefruit juice. Your prescriber may decide that taking these drugs together will benefit you. If you experience a worsening of side effects, contact your health care professional.
    • Notes for Professionals: Caution is advised when administering tenofovir, PMPA, a P-glycoprotein (P-gp) substrate, concurrently with inhibitors of P-gp, such as grapefruit juice. Coadministration may result in increased absorption of tenofovir. Monitor for tenofovir-associated adverse reactions.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.