• No image available for this medication

    • THIOTEPA (Generic for TEPADINA)

THIOTEPA (thye oh TEP a) is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat many types of cancer like breast cancer, ovarian cancer, and bladder cancer and to treat fluid build-up caused by some cancers. It is also used to reduce the risk of graft rejection after a bone morrow transplant in pediatric patients with beta-thalassemia.

THIOTEPA (Generic for TEPADINA) Lifestyle Interactions

  • Thiotepa 15mg, Powder for solution for injection

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not take thiotepa with grapefruit or grapefruit juice. Taking thiotepa and grapefruit juice together may cause Thiotepa to not work as well for you.
    • Notes for Professionals: Avoid the concomitant use of thiotepa and grapefruit juice; reduced metabolism to the active thiotepa metabolite may result in decreased thiotepa efficacy. In vitro, thiotepa is metabolized via CYP3A4 to the active metabolite, TEPA; grapefruit juice is a strong CYP3A4 inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.