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    • REVATIO (Brand for SILDENAFIL CITRATE)

    • QTY 30
    • 20 MG
    • Tablet

SILDENAFIL (sil DEN a fil) treats pulmonary arterial hypertension (PAH), a condition that causes high blood pressure in the lungs. It works by relaxing your blood vessels and lowering the blood pressure in your lungs, which makes it easier for your heart to pump blood to the rest of your body. It can also help you breathe easier and be more active.

REVATIO (Brand for SILDENAFIL CITRATE) Lifestyle Interactions

  • Sildenafil Citrate 20mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Moderate
    • Notes for Consumers: Grapefruit juice and grapefruit-containing foods may increase the side effects of Sildenafil. Do not significantly alter grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible. When taking Sildenafil, contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your usual heart beat (fast, slow, or irregular heart beat).
    • Notes for Professionals: Sildenafil is metabolized via the cytochrome CYP 3A4 isozyme. Grapefruit juice contains a compound that inhibits CYP3A4 in enterocytes in the GI tract. Sildenafil levels may increase; it is possible that sildenafil-induced side effects could also be increased in some individuals. One study has confirmed a potential interaction; sildenafil's AUC increased 23 percent with coadministration of grapefruit juice.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.