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RELION PRIME Lifestyle Interactions
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Fesoterodine fumarate 4mg, Oral tablet, extended release
• Interaction: Grapefruit juice• Severity: Moderate• Notes for Consumers: Side effects from Fesoterodine may get worse if you take grapefruit juice. Do not significantly alter your intake of grapefruit or grapefruit juice while taking Fesoterodine. Discuss any new or worsening side effects, such as constipation, dizziness, difficulty with urination, dry mouth and eyes, changes in vision, fast heartbeat, or confusion, with your health care provider.• Notes for Professionals: Fesoterodine is rapidly hydrolyzed to its active metabolite, 5-hydroxymethyltolterodine, which is metabolized via hepatic CYP3A4. In theory, the CYP3A4 inhibitory effects of grapefruit juice may result in an increase in plasma concentrations of 5-hydroxymethyltolterodine.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
