• Image of Phenergan medication

    • PROMETHAZINE HCL (Generic for PHENERGAN)

    • QTY 30
    • 25 MG
    • Tablet

PROMETHAZINE (proe METH a zeen) prevents and treats the symptoms of an allergic reaction. It works by blocking histamine, a substance released by the body during an allergic reaction. It may also help you relax, go to sleep, and relieve nausea, vomiting, or pain before or after procedures. It can also prevent and treat motion sickness. It works by helping your nervous system calm down by blocking substances in the body that may cause nausea and vomiting. It belongs to a group of medications called antihistamines.

PROMETHAZINE HCL (Generic for PHENERGAN) Lifestyle Interactions

  • Divalproex Sodium 500mg, Oral tablet, gastro-resistant

    • Interaction: Alcohol
    • Severity: Moderate
    • Notes for Consumers: Ethanol may decrease the actions of Valproic Acid, Divalproex Sodium (Depakote, Depakene). In general, it is best to limit or avoid alcoholic beverages while on Valproic acid or Divalproex. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery while drinking alcoholic beverages.
    • Notes for Professionals: Concomitant use of ethanol or other CNS depressants with valproic acid can cause additive CNS depression.

  • Divalproex Sodium 500mg, Oral tablet, gastro-resistant

    • Interaction: Marijuana
    • Severity: Moderate
    • Notes for Consumers: The effects of marijuana may be increased and side effects may get worse if it is combined with this medicine. Do not drive or operate machinery until you know how this combination will affect you. Contact your health care provider right away if you notice slurred speech, confusion, severe drowsiness, increased heart rate, or any other new or unusual side effects.
    • Notes for Professionals: The incidence of marijuana associated adverse effects may change following coadministration with valproic acid, divalproex sodium. Valproic acid is an inhibitor of CYP2C9, an isoenzyme partially responsible for the metabolism of marijuana's most psychoactive compound, delta-9-tetrahydrocannabinol (Delta-9-THC). When given concurrently with valproic acid, the amount of Delta-9-THC converted to the active metabolite 11-hydroxy-delta-9-tetrahydrocannabinol (11-OH-THC) may be reduced. These changes in Delta-9-THC and 11-OH-THC plasma concentrations may result in an altered marijuana adverse event profile.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.