PRAZIQUANTEL (Generic for BILTRICIDE)

Praziquantel 600mg, Oral tablet

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: In general, most foods are safe to take with Praziquantel and in fact, the drug should be taken with some liquid along with a meal for best effect. Grapefruit juice may increase the effects of Praziquantel by increasing the blood levels of Praziquantel. Although an interaction with grapefruit juice is possible, the interaction is not necessarily a harmful one. Since there is limited data about this interaction however, try to keep your grapefruit juice intake steady while taking Praziquantel. If you regularly drink grapefruit juice in large amounts, notify your prescriber if you note any new or worsening potential Praziquantel side effects, like generally not feeling well, headache, dizziness, or abdomen discomfort with or without nausea.

· Notes for Professionals: Coadministration of grapefruit juice with praziquantel has been reported to increase blood levels and AUC of praziquantel, which may be advantageous in the treatment of various parasitic infections. However, more study is needed to determine if this interaction is beneficial or harmful.

Praziquantel 600mg, Oral tablet

Alcohol

· Severity: Major

· Notes for Consumers: Alcohol use should be avoided while you are taking Praziquantel treatment, as additive dizziness and sedation may occur. Do not to drive a car and not to operate machinery on the day of praziquantel treatment and the following day.

· Notes for Professionals: The use of praziquantel may cause CNS side effects, such as dizziness and tiredness, which may be potentiated by alcohol. It is prudent to have patients avoid alcohol ingestion during treatment. Patients should be warned not to drive a car and not to operate machinery on the day of praziquantel treatment and the following day.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>