PADCEV

Enfortumab vedotin 20mg, Powder for solution for injection

Grapefruit juice

· Severity: Major

· Notes for Consumers: Side effects from Enfortumab Vedotin may get worse if you drink Grapefruit Juice, including nausea, vomiting, mouth sores, and pain, tingling, numbness in the hands or feet. Discuss any new or worsening side effects with your health care provider. Contact your healthcare provider immediately if you notice fever or chills, sore throat, bruising or pinpoint red spots on the skin.

· Notes for Professionals: Advise patients to avoid grapefruit juice while taking enfortumab vedotin due to the risk of increased enfortumab vedotin exposure. Enfortumab vedotin is a CYP3A4 substrate and grapefruit juice is a strong CYP3A4 inhibitor.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.