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MAVYRET Lifestyle Interactions
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Glecaprevir 100mg, Pibrentasvir 40mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Moderate• Notes for Consumers: Do not take Grapefruit juice with Glecaprevir without approval from your prescriber. Side effects may get worse if you drink Grapefruit juice while taking Glecaprevir. Discuss any new or worsening side effects with your health care provider.• Notes for Professionals: Caution is advised with the coadministration of glecaprevir and grapefruit juice as coadministration may increase serum concentrations of glecaprevir and increase the risk of adverse effects. Glecaprevir is a substrate of P-glycoprotein (P-gp); grapefruit juice is a P-gp inhibitor.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.