• Image of Arava medication Image of Arava medication
    • LEFLUNOMIDE (Generic for ARAVA)

    • QTY 90
    • 20 MG
    • Tablet
    • Near  77381

LEFLUNOMIDE (le FLOO na mide) is for rheumatoid arthritis.


LEFLUNOMIDE (Generic for ARAVA) Lifestyle Interactions

  • Leflunomide 20mg, Oral tablet

    Interaction: Alcohol
    Severity: Major
    Notes for Consumers: Avoid alcohol-containing drinks while taking Leflunomide. Severe liver side effects due to Leflunomide may get worse if you regularly drink alcohol-containing drinks. Report any abdominal pain, anorexia, increased fatigue, nausea-vomiting, yellowing of skin or eyes, or continual darkening of the urine to your health care professional promptly.
    Notes for Professionals: The hepatotoxicity of leflunomide may be increased if combined with heavy ethanol use.
  • Leflunomide 20mg, Oral tablet

    Interaction: Marijuana
    Severity: Moderate
    Notes for Consumers: The effects of marijuana may be increased and side effects may get worse if it is combined with this medicine. Do not drive or operate machinery until you know how this combination will affect you. Contact your health care provider right away if you notice slurred speech, confusion, severe drowsiness, increased heart rate, or any other new or unusual side effects.
    Notes for Professionals: The incidence of marijuana associated adverse effects may change following coadministration with leflunomide. Leflunomide is an inhibitor of CYP2C9, an isoenzyme partially responsible for the metabolism of marijuana's most psychoactive compound, delta-9-tetrahydrocannabinol (Delta-9-THC). When given concurrently with leflunomide, the amount of Delta-9-THC converted to the active metabolite 11-hydroxy-delta-9-tetrahydrocannabinol (11-OH-THC) may be reduced. These changes in Delta-9-THC and 11-OH-THC plasma concentrations may result in an altered marijuana adverse event profile.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.