GABAPENTIN ER (Generic for GRALISE)

Gabapentin 300mg, Oral tablet, extended release

Alcohol

· Severity: Major

· Notes for Consumers: Avoid Alcohol while taking this drug. Using this drug along with Alcohol can lead to serious side effects. You may feel drowsy or more tired when taking together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.

· Notes for Professionals: Advise patients to avoid alcohol while taking gabapentin. Concomitant use of alcohol with gabapentin may cause excessive sedation, somnolence, and respiratory depression. Alcohol causes a more rapid release of gabapentin enacarbil from the extended-release tablets that may increase the risk for adverse events. In an in vitro dissolution study, 63% of the gabapentin enacarbil dose was released at 1 hour at the highest ethanol concentration (40%). At a 5% ethanol concentration, 43% of the dose was released at 1 hour.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>