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    • TOREMIFENE CITRATE (Generic for FARESTON)

TOREMIFENE (tore EM i feen) blocks the effects of estrogen. It is used to treat some types of breast cancer.

TOREMIFENE CITRATE (Generic for FARESTON) Lifestyle Interactions

  • Toremifene Citrate 60mg, Oral tablet

    • Interaction: Grapefruit juice
    • Severity: Major
    • Notes for Consumers: Do not eat or drink grapefruit or grapefruit juice while taking Toremifene without talking to your doctor or healthcare professional. Grapefruit can increase the amount of Toremifene in your blood which can increase the risk of a dangerous change in heartbeat or heart rhythm. Contact your prescriber immediately if you experience chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your heart beat (such as a fast or irregular heart beat).
    • Notes for Professionals: Instruct patients to avoid grapefruit juice while receiving toremifene due to increased plasma concentrations of toremifene which may result in QT prolongation. Toremifene is a CYP3A4 substrate that has been shown to prolong the QTc interval in a dose- and concentration-related manner, and grapefruit juice is a strong CYP3A4 inhibitor. Coadministration with another strong CYP3A4 inhibitor increased toremifene exposure by 2.9-fold; exposure to N-demethyltoremifene was reduced by 20%.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.