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    • BRIMONIDINE TARTRATE-TIMOLOL (Generic for COMBIGAN)

    • QTY 10
    • 0.2%-0.5%
    • Drops

BRIMONIDINE; TIMOLOL (bri MOE ni deen; TYE moe lole) is used in the eye to treat open-angle glaucoma and high pressure in the eyes.

BRIMONIDINE TARTRATE-TIMOLOL (Generic for COMBIGAN) Lifestyle Interactions

  • Brimonidine Tartrate 0.2%, Timolol Maleate 0.5%, Ophthalmic drops, solution

    • Interaction: Marijuana
    • Severity: Major
    • Notes for Consumers: Marijuana can decrease the ability of this medicine to control your blood pressure and heart rate. You may need to monitor your blood pressure and heart rate more often to make sure they are well-controlled. If you check your own blood pressure at home and notice an increase in your blood pressure or heart rate, contact your health care provider.
    • Notes for Professionals: Avoid administering marijuana and beta-blockers together as concurrent use may result in decreased beta-blocker efficacy. Marijuana is known to produce significant increases in heart rate and cardiac output lasting for 2-3 hours. Further, rare case reports of myocardial infarction and cardiac arrhythmias have been associated with marijuana use. These marijuana-induced cardiovascular effects may be detrimental to patients requiring treatment with beta-blockers; thus, coadministration of beta-blockers and marijuana should be avoided.

  • Brimonidine Tartrate 0.2%, Timolol Maleate 0.5%, Ophthalmic drops, solution

    • Interaction: Alcohol
    • Severity: Moderate
    • Notes for Consumers: Avoid or minimize your intake of Ethanol (alcohol-containing drinks) while taking Brimonidine Eye Solution. You may feel drowsy or more tired; do not drive or operate machinery while taking these products together.
    • Notes for Professionals: Based on the sedative effects of brimonidine in individual patients, brimonidine administration has potential to enhance the CNS depressants effects of ethanol.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.