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CHLORPROMAZINE (klor PROE ma zeen) treats several kinds of mental health conditions, such as schizophrenia and bipolar disorder. It works by balancing the level of dopamine in your brain, a substance that helps regulate mood. It may also be used to treat nausea and vomiting, prolonged hiccups, episodes of porphyria, and tetanus. It can also help you relax before a procedure. It belongs to a group of medications called antipsychotics.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
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Take this medication by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medication more often than directed. Do not stop taking this medication suddenly. This can cause nausea, vomiting, and dizziness. Ask your care team for advice if you are to stop taking this medication.
Talk to your care team about the use of this medication in children. Special care may be needed. While this medication may be prescribed for children as young as 6 months for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Do not take this medication with any of the following:
-Cisapride
-Dronedarone
-Metoclopramide
-Pimozide
-Saquinavir
-Thioridazine
This medication may also interact with the following:
-Alcohol
-Antihistamines for allergy, cough, and cold
-Atropine
-Certain medications for anxiety or sleep
-Certain medications for bladder problems like oxybutynin, tolterodine
-Certain medications for depression like amitriptyline, fluoxetine, sertraline
-Certain medications for stomach problems like dicyclomine, hyoscyamine
-Certain medications for travel sickness like scopolamine
-Epinephrine
-General anesthetics like halothane, isoflurane, methoxyflurane, propofol
-Levodopa or other medications for Parkinson's disease
-Lithium
-Medications for high blood pressure
-Medications for seizures like phenobarbital, primidone, phenytoin
-Medications that relax muscles for surgery
-Narcotic medications for pain
-Other medications that prolong the QT interval (an abnormal heart rhythm)
-Propranolol
-Warfarin
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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Visit your care team for regular checks on your progress. Tell your care team if symptoms do not start to get better or if they get worse. Do not stop taking except on your care team's advice. You may develop a severe reaction. Your care team will tell you how much medication to take.
You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medication affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.
This medication can cause problems with controlling your body temperature. It can lower the response of your body to cold temperatures. If possible, stay indoors during cold weather. If you must go outdoors, wear warm clothes. It can also lower the response of your body to heat. Do not overheat. Do not over-exercise. Stay out of the sun when possible. If you must be in the sun, wear cool clothing. Drink plenty of water. If you have trouble controlling your body temperature, call your care team right away.
This medication can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
This medication may increase blood sugar. Ask your care team if changes in diet or medications are needed if you have diabetes.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe.
If you are going to have surgery, tell your care team that you are taking this medication.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
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Side effects that you should report to your care team as soon as possible:
-Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
-Infection—fever, chills, cough, or sore throat
-High fever, stiff muscles, increased sweating, fast or irregular heartbeat, and confusion, which may be signs of neuroleptic malignant syndrome
-High prolactin level—unexpected breast tissue growth, discharge from the nipple, change in sex drive or performance, irregular menstrual cycle
-Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
-Low blood pressure—dizziness, feeling faint or lightheaded, blurry vision
-Uncontrolled and repetitive body movements, muscle stiffness or spasms, tremors or shaking, loss of balance or coordination, restlessness, shuffling walk, which may be signs of extrapyramidal symptoms (EPS)
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
-Constipation
-Dizziness
-Drowsiness
-Dry mouth
-Weight gain
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
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