CERDELGA

Eliglustat 84mg, Oral capsule

Grapefruit juice

· Severity: Severe

· Notes for Consumers: Do not take these agents together. Taking these agents together can increase the risk of a dangerous change in heartbeat or heart rhythm. These changes may result in chest pain, dizziness, fainting or falling spells, palpitations, shortness of breath, or a change in your heart beat (such as a fast or irregular heart beat).

· Notes for Professionals: Avoid consumption of grapefruit or grapefruit juice with eliglustat. Grapefruit is a strong CYP3A inhibitor and eliglustat is a CYP3A substrate; consumption may increase exposure to eliglustat and increase the risk of serious adverse events (e.g., QT prolongation and cardiac arrhythmias).

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>