CARISOPRODOL-ASPIRIN-CODEINE

Carisoprodol 200mg, Aspirin 325mg, Codeine Phosphate 16mg, Oral tablet

Grapefruit juice

· Severity: Moderate

· Notes for Consumers: It is recommended that you limit and do not significantly alter your intake of grapefruit or grapefruit juice while taking codeine. Side effects from codeine may get worse if you increase your intake of grapefruit juice. Talk to your doctor first. Contact your doctor right away if you have symptoms of codeine side effects such as slurred speech, confusion, weakness, or trouble breathing. Do not drive or operate machinery until you know how codeine affects you.

· Notes for Professionals: Patients should not significantly alter their intake of grapefruit or grapefruit juice during therapy with codeine. Grapefruit juice, a CYP3A4 inhibitor, may increase plasma concentrations of codeine, a CYP3A4 substrate. This may increase or prolong codeine-related toxicities including respiratory depression. Advise patients accordingly; patient monitoring and dosage adjustments may be necessary if grapefruit is consumed regularly.

Carisoprodol 200mg, Aspirin 325mg, Codeine Phosphate 16mg, Oral tablet

Alcohol

· Severity: Moderate

· Notes for Consumers: Do not drink Alcoholic beverages while taking Carisoprodol. You may feel drowsy or more tired or other more serious side effects (excessive sedation, confusion, difficulty staying alert, or seizures) may occur if you drink alcohol-containing drinks while taking Carisoprodol.

· Notes for Professionals: Carisoprodol can cause additive CNS depression if used concomitantly with other CNS depressants such as alcohol. Dosage adjustments of carisoprodol and/or the concurrent CNS depressant may be necessary.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>