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CALAMINE Lifestyle Interactions
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Ubrogepant 100mg, Oral tablet
• Interaction: Grapefruit juice• Severity: Severe• Notes for Consumers: Do not take Ubrogepant and Grapefruit Juice together. Drinking Grapefruit juice or consuming grapefruit-containing foods while taking Ubrogepant may increase the risk of serious side effects.• Notes for Professionals: Coadministration of ubrogepant and grapefruit juice is contraindicated as concurrent use may increase ubrogepant exposure and the risk of adverse effects. Ubrogepant is a CYP3A4 substrate; grapefruit juice is a strong CYP3A4 inhibitor. Coadministration with another strong CYP3A4 inhibitor resulted in a 9.7-fold increase in the exposure of ubrogepant.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.
