BISMUTH-METRONIDAZOLE-TETRACYC (Generic for PYLERA)

Bismuth Subcitrate Potassium 140mg, Metronidazole 125mg, Tetracycline Hydrochloride 125mg, Oral capsule

Foods High in Iron

· Severity: Major

· Notes for Consumers: Specific food that is high in calcium such as dairy products (cheese, milk, yogurt, or cottage cheese) can decrease the absorption of Tetracycline (Antibiotic) from the stomach. Taking dairy product or other high-calcium foods together together with Tetracycline can decrease the effectiveness of Tetracycline to treat an infection. To limit this interaction, take Tetracycline at least 1 hour before or 2 hours after meals or milk.

· Notes for Professionals: Iron salts that are present in foods and dairy products can form chelates with tetracycline and impair absorption. Administer tetracycline at least one hour prior to or two hours after a meal and/or milk.

Bismuth Subcitrate Potassium 140mg, Metronidazole 125mg, Tetracycline Hydrochloride 125mg, Oral capsule

Alcohol

· Severity: Severe

· Notes for Consumers: Do not drink alcoholic beverages or use medicines that contain Alcohol as an ingredient while taking Metronidazole. This includes products containing Propylene Glycol, a type of alcohol. Continue to avoid Alcohol and Propylene Glycol for about 3 days after stopping Metronidazole. When products containing Alcohol (including medicines with a significant amount of alcohol in them) or Propylene Glycol are taken by patients receiving Metronidazole, an extremely unpleasant reaction is likely. This reaction includes flushing, throbbing headache, nausea, vomiting, sweating, thirst, and other effects that can be severe and last from 30 minutes to several hours. Interactions with Metronidazole vaginal or topical skin products are not likely.

· Notes for Professionals: Advise patients to discontinue alcoholic beverages and other forms of alcohol (including medicines with significant alcohol content and any products containing propylene glycol) before, during, and up to 3 days after therapy with systemic metronidazole. Disulfiram-like side effects including nausea, vomiting, tachycardia, headache, flushing, and abdominal cramps may occur if used together.

Bismuth Subcitrate Potassium 140mg, Metronidazole 125mg, Tetracycline Hydrochloride 125mg, Oral capsule

Calcium-containing foods

· Severity: Major

· Notes for Consumers: Specific food that is high in calcium such as dairy products (cheese, milk, yogurt, or cottage cheese) can decrease the absorption of Tetracycline (Antibiotic) from the stomach. Taking dairy product or other high-calcium foods together together with Tetracycline can decrease the effectiveness of Tetracycline to treat an infection. To limit this interaction, take Tetracycline at least 1 hour before or 2 hours after meals or milk.

· Notes for Professionals: Calcium salts that are present in foods and dairy products can form chelates with tetracycline and impair absorption. Administer tetracycline at least one hour prior to or two hours after a meal and/or milk.

<b>DISCLAIMER:</b><em> This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.</em>