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    • BIJUVA

    • QTY 30
    • 1 MG-100MG
    • Capsule
    • Near  77381

ESTRADIOL; PROGESTERONE (es tra DYE ole; (proe JES ter one) reduces the number and severity of hot flashes due to menopause. It works by increasing levels of the hormones estrogen and progestin in your body. It is a combination of the hormones estrogen and progestin.


BIJUVA Lifestyle Interactions

  • Estradiol 1mg, Progesterone 100mg, Oral capsule

    Interaction: Grapefruit juice
    Severity: Mild
    Notes for Consumers: Grapefruit juice and grapefruit-containing foods may increase the side effects of estrogen in some females, such as nausea, breast tenderness, headache or fluid retention. There may be no interaction. Do not significantly change your grapefruit intake while taking estrogens for hormone replacement therapy or as part of hormonal birth control products. Report any unusual side effects, like unusual non-menstrual vaginal bleeding, promptly for evaluation.
    Notes for Professionals: Grapefruit juice has been reported to decrease the metabolism of some estrogens. Grapefruit juice contains a compound that inhibits CYP3A4 in enterocytes. Estrogen levels may increase by up to 30 percent with chronic use. The clinical significance of the interaction is unknown. It is possible that estrogen induced side effects could be increased in some individuals. Patients should be advised to not significantly alter their grapefruit juice ingestion.When chronically ingesting any CYP3A4 inhibitor ( > 30 days) with estrogens, adequate diagnostic measures, including directed or random endometrial sampling when indicated by signs and symptoms of endometrial hyperplasia, should be undertaken to rule out malignancy in postmenopausal women with undiagnosed persistent or recurring abnormal genital bleeding.
  • Estradiol 1mg, Progesterone 100mg, Oral capsule

    Interaction: High Fat Foods
    Severity: Mild
    Notes for Consumers: In general, there are no food interactions of concern. Progesterone capsules are often taken with food, but do not need to be taken with food.
    Notes for Professionals: Food can increase the bioavailability of progesterone administered orally.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.