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ALOMIRA HP Lifestyle Interactions
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Copanlisib 60mg, Powder for solution for injection
• Interaction: Grapefruit juice• Severity: Major• Notes for Consumers: Do not take Grapefruit juice with Copanlisib without talking to your health care provider. Side effects may get worse if you drink Grapefruit juice while taking Copanlisib. Discuss any new or worsening side effects with your health care provider including high blood pressure, fever or chills, cough, sore throat, pain or trouble passing urine, skin rash, itching, or hives.• Notes for Professionals: Avoid the concomitant use of copanlisib and grapefruit juice if possible; increased copanlisib exposure may occur. If coadministration cannot be avoided, reduce the copanlisib dose to 45 mg and monitor patients for copanlisib-related adverse events (e.g., hypertension, infection, and skin rash). Copanlisib is a CYP3A substrate; grapefruit juice is a strong CYP3A inhibitor.
DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.