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    • ADEMPAS

    • QTY 9
    • 0.5 MG
    • Tablet

RIOCIGUAT (rye oh sig ue at) is used to treat pulmonary hypertension. This medicine may help make exercise and breathing easier.

ADEMPAS Lifestyle Interactions

  • Riociguat 0.5mg, Oral tablet

    • Interaction: Tobacco
    • Severity: Major
    • Notes for Consumers: Tobacco smoke contains substances that may speed the removal of Riociguat from the body. If you smoke, Riociguat may become less effective. If you stop smoking, the amount of Riociguat in the blood may increase. Side effects from Riociguat may get worse. Tell your health care professional if you smoke or if you are going to stop smoking.
    • Notes for Professionals: In patients who smoke tobacco, plasma concentrations of riociguat are reduced by 50 to 60% compared to nonsmokers. Doses > 2.5 mg PO three times a day may be considered in smokers in order to match exposure seen in nonsmoking patients. Safety and efficacy of riociguat in doses > 2.5 mg three times a day have not been established. A dose reduction should be considered in patients who stop smoking.

DISCLAIMER: This drug information content is provided for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physician with any questions regarding a medical condition and to obtain medical advice and treatment. Drug information is sourced from GSDD (Gold Standard Drug Database ) provided by Elsevier.